Ontology highlight
ABSTRACT:
SUBMITTER: Lee K
PROVIDER: S-EPMC4959603 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Angewandte Chemie (International ed. in English) 20160504 26
We report a strategy for using magnetic Janus microparticles to control the stimulation of T cell signaling with single-cell precision. To achieve this, we designed Janus particles that are magnetically responsive on one hemisphere and stimulatory to T cells on the other side. By manipulating the rotation and locomotion of Janus particles under an external magnetic field, we could control the orientation of the particle-cell recognition and thereby the initiation of T cell activation. This study ...[more]