Ontology highlight
ABSTRACT:
SUBMITTER: Itzhak DN
PROVIDER: S-EPMC4959882 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
eLife 20160609
Subcellular localization critically influences protein function, and cells control protein localization to regulate biological processes. We have developed and applied Dynamic Organellar Maps, a proteomic method that allows global mapping of protein translocation events. We initially used maps statically to generate a database with localization and absolute copy number information for over 8700 proteins from HeLa cells, approaching comprehensive coverage. All major organelles were resolved, with ...[more]