Ontology highlight
ABSTRACT:
SUBMITTER: Wang WJ
PROVIDER: S-EPMC4960595 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Wang Wen-Juan WJ Cai Guang-Yan GY Ning Yi-Chun YC Cui Jing J Hong Quan Q Bai Xue-Yuan XY Xu Xiao-Meng XM Bu Ru R Sun Xue-Feng XF Chen Xiang-Mei XM
Scientific reports 20160726
Renal aging is always accompanied by increased oxidative stress. Hydrogen sulfide (H2S) can be up-regulated by 50% dietary restriction (DR) for 7-day and can block mitochondrial oxidative stress. H2S production exerts a critical role in yeast, worm, and fruit fly models of DR-mediated longevity. In this study, we found that renal aging could be attenuated by 30% DR for 6-month (DR-6M) and life-long (DR-LL), but not for 6-week (DR-6W). The expressions of cystathionine-γ-lyase (CGL) and cystathion ...[more]