Per cent emphysema is associated with respiratory and lung cancer mortality in the general population: a cohort study.

ABSTRACT:

Background

Emphysema on CT is a risk factor for all-cause mortality in persons with and without airflow obstruction; however, causes of death associated with emphysema remain uncertain, particularly in the general population.

Aims

To test associations between quantitatively assessed emphysema on CT and cause of death in persons with and without a substantial smoking history.

Methods

The Multi-Ethnic Study of Atherosclerosis recruited 6814 participants, aged 45-84 years and without clinical cardiovascular disease, in 2000-2002. Per cent emphysema was defined on cardiac CT as per cent of lung voxels less than -950 Hounsfield units; emphysema on CT was defined as per cent emphysema above the upper limit of normal. Cause of death was classified by administrative codes. Pr

SUBMITTER: Oelsner EC 

PROVIDER: S-EPMC4960821 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature