Ontology highlight
ABSTRACT:
SUBMITTER: Myers KM
PROVIDER: S-EPMC4961034 | biostudies-literature | 2010 Jan
REPOSITORIES: biostudies-literature
Myers Karyn M KM Carlezon William A WA
Biological psychiatry 20100101 1
<h4>Background</h4>Cues paired with drug administration trigger relapse to drug seeking by inducing conditioned drug craving and withdrawal. Because drug cues hinder abstinence in addicts, therapies that reduce responsiveness to drug cues might facilitate rehabilitation. Extinction is a means of reducing conditioned responses and involves exposure to the conditioned stimulus in the absence of the unconditioned stimulus with which it was paired previously. We examined conditioned withdrawal extin ...[more]