Biodegradable-Polymer-Blend-Based Surgical Sealant with Body-Temperature-Mediated Adhesion.
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ABSTRACT:
SUBMITTER: Behrens AM
PROVIDER: S-EPMC4961426 | biostudies-literature | 2015 Dec
REPOSITORIES: biostudies-literature
Publications
Biodegradable-Polymer-Blend-Based Surgical Sealant with Body-Temperature-Mediated Adhesion.
Behrens Adam M AM Lee Nora G NG Casey Brendan J BJ Srinivasan Priya P Sikorski Michael J MJ Daristotle John L JL Sandler Anthony D AD Kofinas Peter P
Advanced materials (Deerfield Beach, Fla.) 20151110 48
The development of practical and efficient surgical sealants has the propensity to improve operational outcomes. A biodegradable polymer blend is fabricated as a nonwoven fiber mat in situ. After direct deposition onto the tissue of interest, the material transitions from a fiber mat to a film. This transition promotes polymer-substrate interfacial interactions leading to improved adhesion and surgical sealant performance. ...[more]
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