Ontology highlight
ABSTRACT:
SUBMITTER: Han B
PROVIDER: S-EPMC4962078 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Han Bing B Zhang Xu X Feng Zi-Ming ZM Jiang Jian-Shuang JS Li Li L Yang Ya-Nan YN Zhang Pei-Cheng PC
Scientific reports 20160727
Ligubenzocycloheptanone A (1), a novel tricyclic butenolide with a 6/7/5-membered ring skeleton, was isolated from the rhizome of Ligusticum chuanxiong. Its unusual structure was determined using UV, IR, HRESIMS, 1D and 2D NMR data, X-ray diffraction crystallography and by the comparison of experimental and calculated electronic circular dichroism (ECD) spectra. 1 possessed a benzocycloheptanone core featuring butyrolactone, which is rarely observed in nature. A possible biosynthetic pathway was ...[more]