Ontology highlight
ABSTRACT:
SUBMITTER: Savoia P
PROVIDER: S-EPMC4963052 | biostudies-literature | 2016 May
REPOSITORIES: biostudies-literature
Human vaccines & immunotherapeutics 20160218 5
In the last years the onset of new therapies changed the management of malignant melanoma. Anti CTLA-4 antibody ipilimumab was the first drug to achieve a significant improvement in survival of advanced stage melanoma. This new therapeutic agent is characterized by a number of side effects that are totally different from those of traditional chemotherapy, mainly caused by the immune system activation. The purpose of this paper is to underline the central role of ipilimumab in the treatment of me ...[more]