Ontology highlight
ABSTRACT:
SUBMITTER: Zabek T
PROVIDER: S-EPMC4963465 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
Ząbek T T Semik E E Szmatoła T T Oklejewicz B B Fornal A A Bugno-Poniewierska M M
Journal of applied genetics 20151109 3
Methylation profiles across three CpG islands of the RNASEL gene were determined in blood leukocyte samples of Anglo-Arabian and Hucul horses. Bisulfite sequencing revealed hypomethylated state of the RNASEL promoter coinciding with methylated CpG island placed inside the gene. Several CpG sites were identified for which the methylation state was influenced by DNA polymorphism. Two of them showed monoallelic methylation. One of the CpG sites revealed functional polymorphism. A number of partiall ...[more]