Ontology highlight
ABSTRACT:
SUBMITTER: Polireddy K
PROVIDER: S-EPMC4964134 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Journal of Cancer 20160707 11
Pancreatic cancer is one of the most lethal cancers among all malignances, with a median overall survival of <1 year and a 5-year survival of ~5%. The dismal survival rate and prognosis are likely due to lack of early diagnosis, fulminant disease course, high metastasis rate, and disappointing treatment outcome. Pancreatic cancers harbor a variety of genetic alternations that render it difficult to treat even with targeted therapy. Recent studies revealed that pancreatic cancers are highly enric ...[more]