Association of Fluid Accumulation with Clinical Outcomes in Critically Ill Children with Severe Sepsis.

ABSTRACT:

Objective

To evaluate whether early and acquired daily fluid overload (FO), as well as fluctuations in fluid accumulation, were associated with adverse outcomes in critically ill children with severe sepsis.

Methods

This study enrolled 202 children in a pediatric intensive care unit (PICU) with severe sepsis. Early fluid overload was defined as ≥5% fluid accumulation occurring in the first 24 hours of PICU admission. The maximum daily fluid accumulation ≥5% occurring during the next 6 days in patients with at least 48 hours of PICU stay was defined as PICU-acquired daily fluid overload. The fluctuation in fluid accumulation was calculated as the difference between the maximum and the minimum daily fluid accumulation obtained during the first 7 days after admission.

Result

SUBMITTER: Chen J 

PROVIDER: S-EPMC4965086 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature