Ontology highlight
ABSTRACT:
SUBMITTER: Constantinides C
PROVIDER: S-EPMC4965459 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Constantinides Christakis C Murphy Kathy K
Frontiers in cardiovascular medicine 20160729
To-this-date, the exact molecular, cellular, and integrative physiological mechanisms of anesthesia remain largely unknown. Published evidence indicates that anesthetic effects are multifocal and occur in a time-dependent and coordinated manner, mediated via central, local, and peripheral pathways. Their effects can be modulated by a range of variables, and their elicited end-effect on the integrative physiological response is highly variable. This review summarizes the major cellular and molecu ...[more]