Ontology highlight
ABSTRACT:
SUBMITTER: Peng CL
PROVIDER: S-EPMC4966578 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
International journal of nanomedicine 20160725
A novel thermosensitive polymer p(N-isopropylacrylamide-co-poly[ethylene glycol] methyl ether acrylate)-block-poly(epsilon-caprolactone), p(NIPAAM-co-PEGMEA)-b-PCL, was synthesized and developed as nanomicelles. The hydrophobic heat shock protein 90 inhibitor 17-allylamino-17-demethoxygeldanamycin and the photosensitizer cyanine dye infrared-780 were loaded into the core of the micelles to achieve both chemotherapy and photothermal therapy simultaneously at the tumor site. The release of the dru ...[more]