Ontology highlight
ABSTRACT:
SUBMITTER: Yang PL
PROVIDER: S-EPMC4966979 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
Yang Po-Lin PL Hsu Tzu-Han TH Wang Chao-Wen CW Chen Rey-Huei RH
Molecular biology of the cell 20160615 15
The neutral lipids steryl ester and triacylglycerol (TAG) are stored in the membrane-bound organelle lipid droplet (LD) in essentially all eukaryotic cells. It is unclear what physiological conditions require the mobilization or storage of these lipids. Here, we study the budding yeast mutant are1Δ are2Δ dga1Δ lro1Δ, which cannot synthesize the neutral lipids and therefore lacks LDs. This quadruple mutant is delayed at cell separation upon release from mitotic arrest. The cells have abnormal sep ...[more]