Quantitative imaging analysis of posterior fossa ependymoma location in children.

ABSTRACT:

Purpose

Imaging descriptions of posterior fossa ependymoma in children have focused on magnetic resonance imaging (MRI) signal and local anatomic relationships with imaging location only recently used to classify these neoplasms. We developed a quantitative method for analyzing the location of ependymoma in the posterior fossa, tested its effectiveness in distinguishing groups of tumors, and examined potential associations of distinct tumor groups with treatment and prognostic factors.

Methods

Pre-operative MRI examinations of the brain for 38 children with histopathologically proven posterior fossa ependymoma were analyzed. Tumor margin contours and anatomic landmarks were manually marked and used to calculate the centroid of each tumor. Landmarks were used to calculate a t

SUBMITTER: Sabin ND 

PROVIDER: S-EPMC4967400 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature