Ontology highlight
ABSTRACT:
SUBMITTER: Swart EC
PROVIDER: S-EPMC4967479 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Swart Estienne Carl EC Serra Valentina V Petroni Giulio G Nowacki Mariusz M
Cell 20160714 3
The prevailing view of the nuclear genetic code is that it is largely frozen and unambiguous. Flexibility in the nuclear genetic code has been demonstrated in ciliates that reassign standard stop codons to amino acids, resulting in seven variant genetic codes, including three previously undescribed ones reported here. Surprisingly, in two of these species, we find efficient translation of all 64 codons as standard amino acids and recognition of either one or all three stop codons. How, therefore ...[more]