Ontology highlight
ABSTRACT:
SUBMITTER: Prodanov L
PROVIDER: S-EPMC4967935 | biostudies-literature | 2016 Jan
REPOSITORIES: biostudies-literature
Prodanov Ljupcho L Jindal Rohit R Bale Shyam Sundhar SS Hegde Manjunath M McCarty William J WJ Golberg Inna I Bhushan Abhinav A Yarmush Martin L ML Usta Osman Berk OB
Biotechnology and bioengineering 20150826 1
The development of long-term human organotypic liver-on-a-chip models for successful prediction of toxic response is one of the most important and urgent goals of the NIH/DARPA's initiative to replicate and replace chronic and acute drug testing in animals. For this purpose, we developed a microfluidic chip that consists of two microfluidic chambers separated by a porous membrane. The aim of this communication is to demonstrate the recapitulation of a liver sinusoid-on-a-chip, using human cells ...[more]