Ontology highlight
ABSTRACT:
SUBMITTER: Kawamoto K
PROVIDER: S-EPMC4968597 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Kawamoto Keisuke K Miyoshi Hiroaki H Yoshida Noriaki N Nakamura Naoya N Ohshima Koichi K Sone Hirohito H Takizawa Jun J
Cancer science 20160506 6
Genomic alterations and protein expression levels have been established as prognostic factors for survival in patients with diffuse large B-cell lymphoma (DLBCL). In particular, double-hit DLBCL (DHL), which exhibits translocations in MYC and BCL2 and/or BCL6, is known to be associated with a poor prognosis. However, the clinical significance of gene alterations and protein expression levels for MYC, B-cell lymphoma (BCL)2, and BCL6 are unclear. In this study, we analyzed 61 adult patients diagn ...[more]