Ontology highlight
ABSTRACT:
SUBMITTER: Honda S
PROVIDER: S-EPMC4968605 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Honda Shohei S Minato Masashi M Suzuki Hiromu H Fujiyoshi Masato M Miyagi Hisayuki H Haruta Masayuki M Kaneko Yasuhiko Y Hatanaka Kanako C KC Hiyama Eiso E Kamijo Takehiko T Okada Tadao T Taketomi Akinobu A
Cancer science 20160427 6
Hepatoblastoma (HB) is very rare but the most common malignant neoplasm of the liver occurring in children. Despite improvements in therapy, outcomes for patients with advanced HB that is refractory to standard preoperative chemotherapy remain unsatisfactory. To improve the survival rate among this group, identification of novel prognostic markers and therapeutic targets is needed. We have previously reported that altered DNA methylation patterns are of biological and clinical importance in HB. ...[more]