Chemical and biological investigation of the fungus Pulveroboletus ravenelii.
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ABSTRACT:
SUBMITTER: Duncan CJ
PROVIDER: S-EPMC4969011 | biostudies-literature | 2003 Jan
REPOSITORIES: biostudies-literature
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Chemical and biological investigation of the fungus Pulveroboletus ravenelii.
Duncan Christine J G CJ Cuendet Muriel M Fronczek Frank R FR Pezzuto John M JM Mehta Rajendra G RG Hamann Mark T MT Ross Samir A SA
Journal of natural products 20030101 1
Two new compounds, pulveraven A (1) and pulveraven B (2), as well as vulpinic acid (3) and its previously unreported polymorph were isolated from the fruiting body of Pulveroboletus ravenelii. The structures were determined using a combination of NMR, MS, IR, optical rotation, molecular modeling, and X-ray analysis. The isolates were evaluated for antimicrobial activity as well as their potential to inhibit cyclooxygenase (COX) activity and carcinogen-induced preneoplastic lesion formation with ...[more]
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