Ontology highlight
ABSTRACT:
SUBMITTER: Sun HN
PROVIDER: S-EPMC4971128 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Sun Hu-Nan HN Shen Gui-Nan GN Jin Yong-Zhe YZ Jin Yu Y Han Ying-Hao YH Feng Li L Liu Lei L Jin Mei-Hua MH Luo Ying-Hua YH Kwon Tea-Ho TH Cui Yu-Dong YD Jin Cheng-Hao CH
Heliyon 20160720 7
<h4>Aims</h4>To verify the effects of several 5,8-dimethoxy-1,4-naphthoquinone (DMNQ) derivatives on LPS-induced NO production, cellular ROS levels and cytokine expression in BV-2 microglial cells.<h4>Main methods</h4>An MTT assay and FACS flow cytometry were performed to assess the cellular viability and apoptosis and cellular ROS levels, respectively. To examine the expression of pro-inflammatory cytokines and cellular signaling pathways, semi-quantitative RT-PCR and Western blotting were also ...[more]