Ontology highlight
ABSTRACT:
SUBMITTER: Hardonniere K
PROVIDER: S-EPMC4973274 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
Hardonnière Kévin K Saunier Elise E Lemarié Anthony A Fernier Morgane M Gallais Isabelle I Héliès-Toussaint Cécile C Mograbi Baharia B Antonio Samantha S Bénit Paule P Rustin Pierre P Janin Maxime M Habarou Florence F Ottolenghi Chris C Lavault Marie-Thérèse MT Benelli Chantal C Sergent Odile O Huc Laurence L Bortoli Sylvie S Lagadic-Gossmann Dominique D
Scientific reports 20160804
Cancer cells display alterations in many cellular processes. One core hallmark of cancer is the Warburg effect which is a glycolytic reprogramming that allows cells to survive and proliferate. Although the contributions of environmental contaminants to cancer development are widely accepted, the underlying mechanisms have to be clarified. Benzo[a]pyrene (B[a]P), the prototype of polycyclic aromatic hydrocarbons, exhibits genotoxic and carcinogenic effects, and it is a human carcinogen according ...[more]