Ameloblastoma Phenotypes Reflected in Distinct Transcriptome Profiles.
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ABSTRACT:
SUBMITTER: Hu S
PROVIDER: S-EPMC4974613 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
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Ameloblastoma Phenotypes Reflected in Distinct Transcriptome Profiles.
Hu Shijia S Parker Joel J Divaris Kimon K Padilla Ricardo R Murrah Valerie V Wright John Timothy JT
Scientific reports 20160805
Ameloblastoma is a locally invasive benign neoplasm derived from odontogenic epithelium and presents with diverse phenotypes yet to be characterized molecularly. High recurrence rates of 50-80% with conservative treatment in some sub-types warrants radical surgical resections resulting in high morbidity. The objective of the study was to characterize the transcriptome of ameloblastoma and identify relevant genes and molecular pathways using normal odontogenic tissue (human "dentome") for compari ...[more]
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