Ontology highlight
ABSTRACT:
SUBMITTER: Love KR
PROVIDER: S-EPMC4974788 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
BMC genomics 20160805
<h4>Background</h4>Pichia pastoris has emerged as an important alternative host for producing recombinant biopharmaceuticals, owing to its high cultivation density, low host cell protein burden, and the development of strains with humanized glycosylation. Despite its demonstrated utility, relatively little strain engineering has been performed to improve Pichia, due in part to the limited number and inconsistent frameworks of reported genomes and transcriptomes. Furthermore, the co-mingling of g ...[more]