Ontology highlight
ABSTRACT:
SUBMITTER: Suyama S
PROVIDER: S-EPMC4977585 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
Suyama Shigetomo S Maekawa Fumihiko F Maejima Yuko Y Kubota Naoto N Kadowaki Takashi T Yada Toshihiko T
Scientific reports 20160809
Adiponectin regulates glucose and lipid metabolism, acting against metabolic syndrome and atherosclerosis. Accumulating evidence suggest that adiponectin acts on the brain including hypothalamic arcuate nucleus (ARC), where proopiomelanocortin (POMC) neurons play key roles in feeding regulation. Several studies have examined intracerebroventricular (ICV) injection of adiponectin and reported opposite effects, increase or decrease of food intake. These reports used different nutritional states. T ...[more]