Ontology highlight
ABSTRACT:
SUBMITTER: Jain N
PROVIDER: S-EPMC4978125 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Jain Nieraj N Jia Yali Y Gao Simon S SS Zhang Xinbo X Weleber Richard G RG Huang David D Pennesi Mark E ME
JAMA ophthalmology 20160601 6
<h4>Importance</h4>Novel therapies for choroideremia, an X-linked recessive chorioretinal degeneration, demand a better understanding of the primary site(s) of cellular degeneration. Optical coherence tomography angiography allows for choriocapillaris (CC) imaging. We compared the extent of structural alterations of the CC, retinal pigment epithelium, and photoreceptors with multimodal imaging.<h4>Observations</h4>In a clinical case series conducted from September 15, 2014, through February 5, 2 ...[more]