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Docosahexaenoic acid supplementation (DHA) and the return on investment for pregnancy outcomes.


ABSTRACT: The Kansas University DHA Outcomes Study (KUDOS) found a significant reduction in early preterm births with a supplement of 600mg DHA per day compared to placebo. The objective of this analysis was to determine if hospital costs differed between groups. We applied a post-hoc cost analysis of the delivery hospitalization and all hospitalizations in the following year to 197 mother-infant dyads who delivered at Kansas University Hospital. Hospital cost saving of DHA supplementation amounted to $1678 per infant. Even after adjusting for the estimated cost of providing 600mg/d DHA for 26 weeks ($166.48) and a slightly higher maternal care cost ($26) in the DHA group, the net saving per dyad was $1484. Extrapolating this to the nearly 4 million US deliveries per year suggests universal supplementation with 600mg/d during the last 2 trimesters of pregnancy could save the US health care system up to USD 6 billion.

SUBMITTER: Shireman TI 

PROVIDER: S-EPMC4978141 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature

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Docosahexaenoic acid supplementation (DHA) and the return on investment for pregnancy outcomes.

Shireman T I TI   Kerling E H EH   Gajewski B J BJ   Colombo J J   Carlson S E SE  

Prostaglandins, leukotrienes, and essential fatty acids 20160513


The Kansas University DHA Outcomes Study (KUDOS) found a significant reduction in early preterm births with a supplement of 600mg DHA per day compared to placebo. The objective of this analysis was to determine if hospital costs differed between groups. We applied a post-hoc cost analysis of the delivery hospitalization and all hospitalizations in the following year to 197 mother-infant dyads who delivered at Kansas University Hospital. Hospital cost saving of DHA supplementation amounted to $16  ...[more]

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