Ontology highlight
ABSTRACT:
SUBMITTER: Lin KW
PROVIDER: S-EPMC4978223 | biostudies-literature | 2015 Dec
REPOSITORIES: biostudies-literature
Lin Kathleen Watson KW Wroolie Tonita E TE Robakis Thalia T Rasgon Natalie L NL
Psychiatry research 20151022 3
Previous studies suggest that insulin-sensitizing agents could play a significant role in the treatment of major depression, particularly depression in patients with documented insulin resistance or those who are resistant to standard psychopharmacological approaches. This study aimed to assess the effects on depressive symptoms with adjuvant treatment with the PPARγ-agonist pioglitazone. Patients (N=37) with non-psychotic, non-remitting depression receiving standard psychiatric regimens for dep ...[more]