Ontology highlight
ABSTRACT:
SUBMITTER: Mohn KG
PROVIDER: S-EPMC4978372 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
Mohn Kristin Greve-Isdahl KG Brokstad Karl Albert KA Pathirana Rishi D RD Bredholt Geir G Jul-Larsen Åsne Å Trieu Mai Chi MC Lartey Sarah Larteley SL Montomoli Emanuele E Tøndel Camilla C Aarstad Hans Jørgen HJ Cox Rebecca Jane RJ
The Journal of infectious diseases 20160530 5
<h4>Background</h4>Tonsils play a key role in eliciting immune responses against respiratory pathogens. Little is known about how tonsils contribute to the local immune response after intranasal vaccination. Here, we uniquely report the mucosal humoral responses in tonsils and saliva after intranasal live attenuated influenza vaccine (LAIV) vaccination in children.<h4>Methods</h4>Blood, saliva, and tonsils samples were collected from 39 children before and after LAIV vaccination and from 16 age- ...[more]