Ontology highlight
ABSTRACT:
SUBMITTER: Tai MC
PROVIDER: S-EPMC4979017 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
Tai Mei Chee MC Yanagisawa Kiyoshi K Nakatochi Masahiro M Hotta Naoe N Hosono Yasuyuki Y Kawaguchi Koji K Naito Mariko M Taniguchi Hiroyuki H Wakai Kenji K Yokoi Kohei K Takahashi Takashi T
Scientific reports 20160810
Accumulated evidence indicates that various types of miRNA are aberrantly expressed in lung cancer and secreted into the bloodstream. For this study, we constructed a serum diagnostic classifier based on detailed bioinformatics analysis of miRNA profiles from a training cohort of 143 lung adenocarcinoma patients and 49 healthy subjects, resulting in a 20 miRNA-based classifier. Validation performed with an independent cohort of samples from lung adenocarcinoma patients (n = 110), healthy subject ...[more]