Ontology highlight
ABSTRACT:
SUBMITTER: Chiang C
PROVIDER: S-EPMC4979219 | biostudies-literature | 2012 Jan
REPOSITORIES: biostudies-literature
Chiang Chunyi C Karuri Stella W SW Kshatriya Pradnya P PP Schwartz Jeffrey J Schwarzbauer Jean E JE Karuri Nancy W NW
Langmuir : the ACS journal of surfaces and colloids 20111206 1
We report a robust strategy for conjugating mixtures of two or more protein domains to nonfouling polyurethane surfaces. In our strategy, the carbamate groups of polyurethane are reacted with zirconium alkoxide from the vapor phase to give a surface-bound oxide that serves as a chemical layer that can be used to bond organics to the polymer substrate. A hydroxyalkylphosphonate monolayer was synthesized on this layer, which was then used to covalently bind primary amine groups in protein domains ...[more]