Ontology highlight
ABSTRACT:
SUBMITTER: Guo Y
PROVIDER: S-EPMC4979676 | biostudies-literature | 2016 Apr
REPOSITORIES: biostudies-literature
Angewandte Chemie (Weinheim an der Bergstrasse, Germany) 20160315 15
A highly efficient cap-exchange approach for preparing compact, dense polyvalent mannose-capped quantum dots (QDs) has been developed. The resulting QDs have been successfully used to probe multivalent interactions of HIV/Ebola receptors DC-SIGN and DC-SIGNR (collectively termed as DC-SIGN/R) using a sensitive, ratiometric Förster resonance energy transfer (FRET) assay. The QD probes specifically bind DC-SIGN, but not its closely related receptor DC-SIGNR, which is further confirmed by its speci ...[more]