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Molecular Imaging of Biomarkers in Breast Cancer.


ABSTRACT: The success of breast cancer therapy is ultimately defined by clinical endpoints such as survival. It is valuable to have biomarkers that can predict the most efficacious therapies or measure response to therapy early in the course of treatment. Molecular imaging has a promising role in complementing and overcoming some of the limitations of traditional biomarkers by providing the ability to perform noninvasive, repeatable whole-body assessments. The potential advantages of imaging biomarkers are obvious and initial clinical studies have been promising, but proof of clinical utility still requires prospective multicenter clinical trials.

SUBMITTER: Ulaner GA 

PROVIDER: S-EPMC4979972 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature

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Molecular Imaging of Biomarkers in Breast Cancer.

Ulaner Gary A GA   Riedl Chris C CC   Dickler Maura N MN   Jhaveri Komal K   Pandit-Taskar Neeta N   Weber Wolfgang W  

Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20160201


The success of breast cancer therapy is ultimately defined by clinical endpoints such as survival. It is valuable to have biomarkers that can predict the most efficacious therapies or measure response to therapy early in the course of treatment. Molecular imaging has a promising role in complementing and overcoming some of the limitations of traditional biomarkers by providing the ability to perform noninvasive, repeatable whole-body assessments. The potential advantages of imaging biomarkers ar  ...[more]

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