Ontology highlight
ABSTRACT:
SUBMITTER: Saha P
PROVIDER: S-EPMC4981296 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
Therapeutic advances in medical oncology 20160710 5
Triple-negative breast cancer (TNBC) is a heterogeneous disease in which tumors are defined by lack of expression of the estrogen receptor (ER), the progesterone receptor (PR), and the human epidermal growth factor receptor 2 (HER2) receptor. No targeted therapies are available for the treatment of TNBC, and chemotherapy remains the standard of care. Gene expression profiling has identified six distinct molecular subtypes of TNBC. The identification of novel targets, coupled with the development ...[more]