Ontology highlight
ABSTRACT:
SUBMITTER: Donohue MP
PROVIDER: S-EPMC4981883 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Physical chemistry chemical physics : PCCP 20160601 22
Aside from a double helix, deoxyribonucleic acid (DNA) folds into non-canonical structures, one of which is the guanine quadruplex. Cationic porphyrins bind guanine quadruplexes, but the effects of ligand binding on the structure of guanine quadruplexes with more than four contiguous guanine quartets remains to be fully elucidated. Double electron-electron resonance (DEER) spectroscopy conducted at 9.5 GHz (X-band) using broadband, shaped inversion pulses was used to measure the distances betwee ...[more]