Ontology highlight
ABSTRACT:
SUBMITTER: Tian B
PROVIDER: S-EPMC4982680 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
PLoS computational biology 20160812 8
Terpenoid synthases create diverse carbon skeletons by catalyzing complex carbocation rearrangements, making them particularly challenging for enzyme function prediction. To begin to address this challenge, we have developed a computational approach for the systematic enumeration of terpenoid carbocations. Application of this approach allows us to systematically define a nearly complete chemical space for the potential carbon skeletons of products from monoterpenoid synthases. Specifically, 1875 ...[more]