Ontology highlight
ABSTRACT:
SUBMITTER: Santos FL
PROVIDER: S-EPMC4982698 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Santos Fred Luciano Neves FL Celedon Paola Alejandra Fiorani PA Zanchin Nilson Ivo Tonin NI Brasil Tatiana de Arruda Campos Tde A Foti Leonardo L Souza Wayner Vieira de WV Silva Edmilson Domingos ED Gomes Yara de Miranda Yde M Krieger Marco Aurélio MA
PloS one 20160812 8
The performance of serologic tests in chronic Chagas disease diagnosis largely depends on the type and quality of the antigen preparations that are used for detection of anti-Trypanosoma cruzi antibodies. Whole-cell T. cruzi extracts or recombinant proteins have shown variation in the performance and cross-reactivity. Synthetic chimeric proteins comprising fragments of repetitive amino acids of several different proteins have been shown to improve assay performances to detect Chagasic infections ...[more]