Endocrine-specific NIR fluorophores for adrenal gland targeting.
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ABSTRACT:
SUBMITTER: Ashitate Y
PROVIDER: S-EPMC4982771 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
Publications
Endocrine-specific NIR fluorophores for adrenal gland targeting.
Ashitate Yoshitomo Y Levitz Andrew A Park Min Ho MH Hyun Hoon H Venugopal Vivek V Park GwangLi G El Fakhri Georges G Henary Maged M Gioux Sylvain S Frangioni John V JV Choi Hak Soo HS
Chemical communications (Cambridge, England) 20160801 67
The adrenal glands (AGs) are relatively small yet require definitive identification during their resection, or more commonly their avoidance. To enable image-guided surgery involving the AGs, we have developed novel near-infrared (NIR) fluorophores that target the AGs after a single intravenous injection, which provided dual-NIR image-guided resection or avoidance of the AGs during both open and minimally-invasive surgery. ...[more]
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