Ontology highlight
ABSTRACT:
SUBMITTER: Heijnsdijk EA
PROVIDER: S-EPMC4982868 | biostudies-literature | 2012 Aug
REPOSITORIES: biostudies-literature
Heijnsdijk Eveline A M EA Wever Elisabeth M EM Auvinen Anssi A Hugosson Jonas J Ciatto Stefano S Nelen Vera V Kwiatkowski Maciej M Villers Arnauld A Páez Alvaro A Moss Sue M SM Zappa Marco M Tammela Teuvo L J TL Mäkinen Tuukka T Carlsson Sigrid S Korfage Ida J IJ Essink-Bot Marie-Louise ML Otto Suzie J SJ Draisma Gerrit G Bangma Chris H CH Roobol Monique J MJ Schröder Fritz H FH de Koning Harry J HJ
The New England journal of medicine 20120801 7
<h4>Background</h4>After 11 years of follow-up, the European Randomized Study of Screening for Prostate Cancer (ERSPC) reported a 29% reduction in prostate-cancer mortality among men who underwent screening for prostate-specific antigen (PSA) levels. However, the extent to which harms to quality of life resulting from overdiagnosis and treatment counterbalance this benefit is uncertain.<h4>Methods</h4>On the basis of ERSPC follow-up data, we used Microsimulation Screening Analysis (MISCAN) to pr ...[more]