Ontology highlight
ABSTRACT:
SUBMITTER: Tasic B
PROVIDER: S-EPMC4985242 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
Tasic Bosiljka B Menon Vilas V Nguyen Thuc Nghi TN Kim Tae Kyung TK Jarsky Tim T Yao Zizhen Z Levi Boaz B Gray Lucas T LT Sorensen Staci A SA Dolbeare Tim T Bertagnolli Darren D Goldy Jeff J Shapovalova Nadiya N Parry Sheana S Lee Changkyu C Smith Kimberly K Bernard Amy A Madisen Linda L Sunkin Susan M SM Hawrylycz Michael M Koch Christof C Zeng Hongkui H
Nature neuroscience 20160104 2
Nervous systems are composed of various cell types, but the extent of cell type diversity is poorly understood. We constructed a cellular taxonomy of one cortical region, primary visual cortex, in adult mice on the basis of single-cell RNA sequencing. We identified 49 transcriptomic cell types, including 23 GABAergic, 19 glutamatergic and 7 non-neuronal types. We also analyzed cell type-specific mRNA processing and characterized genetic access to these transcriptomic types by many transgenic Cre ...[more]