Asbestos Fiber Preparation Methods Affect Fiber Toxicity.
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ABSTRACT:
SUBMITTER: Salamatipour A
PROVIDER: S-EPMC4985249 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Publications
Asbestos Fiber Preparation Methods Affect Fiber Toxicity.
Salamatipour Ashkan A Mohanty Sanjay K SK Pietrofesa Ralph A RA Vann David R DR Christofidou-Solomidou Melpo M Willenbring Jane K JK
Environmental science & technology letters 20160614 7
To measure the toxic potential of asbestos fibers-a known cause of asbestosis, lung cancer, and malignant mesothelioma-asbestos minerals are generally first ground down to small fibers, but it is unknown whether the grinding condition itself changes the fiber toxicity. To evaluate this, we ground chrysotile ore with or without water for 5-30 min and quantified asbestos-induced reactive oxygen species generation in elicited murine peritoneal macrophages as an indicator of fiber toxicity. The toxi ...[more]
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