Insufficient chunk concatenation may underlie changes in sleep-dependent consolidation of motor sequence learning in older adults.
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ABSTRACT:
SUBMITTER: Bottary R
PROVIDER: S-EPMC4986853 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
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Insufficient chunk concatenation may underlie changes in sleep-dependent consolidation of motor sequence learning in older adults.
Bottary Ryan R Sonni Akshata A Wright David D Spencer Rebecca M C RM
Learning & memory (Cold Spring Harbor, N.Y.) 20160816 9
Sleep enhances motor sequence learning (MSL) in young adults by concatenating subsequences ("chunks") formed during skill acquisition. To examine whether this process is reduced in aging, we assessed performance changes on the MSL task following overnight sleep or daytime wake in healthy young and older adults. Young adult performance enhancement was correlated with nREM2 sleep, and facilitated by preferential improvement of slowest within-sequence transitions. This effect was markedly reduced i ...[more]
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