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Light-controlled active release of photocaged ciprofloxacin for lipopolysaccharide-targeted drug delivery using dendrimer conjugates.


ABSTRACT: We report an active delivery mechanism targeted specifically to Gram(-) bacteria based on the photochemical release of photocaged ciprofloxacin carried by a cell wall-targeted dendrimer nanoconjugate.

SUBMITTER: Wong PT 

PROVIDER: S-EPMC4987215 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature

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Light-controlled active release of photocaged ciprofloxacin for lipopolysaccharide-targeted drug delivery using dendrimer conjugates.

Wong Pamela T PT   Tang Shengzhuang S   Mukherjee Jhindan J   Tang Kenny K   Gam Kristina K   Isham Danielle D   Murat Claire C   Sun Rachel R   Baker James R JR   Choi Seok Ki SK  

Chemical communications (Cambridge, England) 20160801 68


We report an active delivery mechanism targeted specifically to Gram(-) bacteria based on the photochemical release of photocaged ciprofloxacin carried by a cell wall-targeted dendrimer nanoconjugate. ...[more]

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