Ontology highlight
ABSTRACT:
SUBMITTER: Cheung CW
PROVIDER: S-EPMC4990657 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
Nature communications 20160812
(Hetero)Aryl amines, an important class of organic molecules in medicinal chemistry, are most commonly synthesized from anilines, which are in turn synthesized by hydrogenation of nitroarenes. Amine synthesis directly from nitroarenes is attractive due to improved step economy and functional group compatibility. Despite these potential advantages, there is yet no general method for the synthesis of (hetero)aryl amines by carbon-nitrogen cross-coupling of nitroarenes. Here we report the reductive ...[more]