Ontology highlight
ABSTRACT:
SUBMITTER: Dobrzynska A
PROVIDER: S-EPMC4991244 | biostudies-literature | 2016 May
REPOSITORIES: biostudies-literature
Dobrzynska Agnieszka A Gonzalo Susana S Shanahan Catherine C Askjaer Peter P
Nucleus (Austin, Tex.) 20160509 3
The nuclear lamina (NL) is a structural component of the nuclear envelope and makes extensive contacts with integral nuclear membrane proteins and chromatin. These interactions are critical for many cellular processes, such as nuclear positioning, perception of mechanical stimuli from the cell surface, nuclear stability, 3-dimensional organization of chromatin and regulation of chromatin-binding proteins, including transcription factors. The NL is present in all nucleated metazoan cells but its ...[more]