Ontology highlight
ABSTRACT:
SUBMITTER: Zoico E
PROVIDER: S-EPMC4991449 | biostudies-literature | 2016 Apr
REPOSITORIES: biostudies-literature
Zoico Elena E Darra Elena E Rizzatti Vanni V Budui Simona S Franceschetti Guido G Mazzali Gloria G Rossi Andrea P AP Fantin Francesco F Menegazzi Marta M Cinti Saverio S Zamboni Mauro M
Oncotarget 20160401 15
A significant epidemiological association between obesity and pancreatic ductal adenocarcinoma (PDAC) has previously been described, as well as a correlation between the degree of pancreatic steatosis, PDAC risk and prognosis. The underlying mechanisms are still not completely known.After co-culture of 3T3-L1 adipocytes and MiaPaCa2 with an in vitro transwell system we observed the appearance of fibroblast-like cells, along with a decrease in number and size of remaining adipocytes. RT-PCR analy ...[more]