Utility of recombinant fragment C for assessment of anti-tetanus antibodies in plasma.
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ABSTRACT:
SUBMITTER: Ramakrishnan G
PROVIDER: S-EPMC4991549 | biostudies-literature | 2015 May
REPOSITORIES: biostudies-literature
Publications
Utility of recombinant fragment C for assessment of anti-tetanus antibodies in plasma.
Ramakrishnan Girija G Pedersen Karl K Guenette Denis D Sink Joyce J Haque Rashidul R Petri William A WA Herbein Joel J Gilchrist Carol A CA
Diagnostic microbiology and infectious disease 20150207 1
Anti-tetanus antibodies in biological samples are typically detected using an enzyme-linked immunosorbent assay based on toxoided tetanus neurotoxin as antigen. We demonstrate that recombinantly produced fragment C of the toxin heavy chain is an effective alternative antigen for assessment of tetanus-immune status in plasma samples. ...[more]
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