Ontology highlight
ABSTRACT:
SUBMITTER: Jones JR
PROVIDER: S-EPMC4991845 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Jones Jeff R JR McMahon Douglas G DG
PeerJ 20160809
The brain's biological clock, the suprachiasmatic nucleus (SCN), exhibits endogenous 24-hour rhythms in gene expression and spontaneous firing rate; however, the functional relationship between these neuronal rhythms is not fully understood. Here, we used a Per1::GFP transgenic mouse line that allows for the simultaneous quantification of molecular clock state and firing rate in SCN neurons to examine the relationship between these key components of the circadian clock. We find that there is a s ...[more]