Ontology highlight
ABSTRACT:
SUBMITTER: Mottl AK
PROVIDER: S-EPMC4993203 | biostudies-literature | 2008 Aug
REPOSITORIES: biostudies-literature
Mottl Amy K AK Shoham David A DA North Kari E KE
Genetics in medicine : official journal of the American College of Medical Genetics 20080801 8
The angiotensin II type 1 receptor (AGTR1) plays an integral role in blood pressure control, and is implicated in the pathogenesis of hypertension. Polymorphisms within this gene have been extensively studied in association with hypertension; however, findings are conflicting. To clarify these data, we conducted a systematic review of association studies of AGTR1 polymorphisms and hypertension, and performed a meta-analysis of the rs5186 variant. Results show that the currently available literat ...[more]