Ontology highlight
ABSTRACT:
SUBMITTER: Zhang L
PROVIDER: S-EPMC4997055 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Zhang Leilei L He Jie J Han Bing B Lu Linna L Fan Jiayan J Zhang He H Ge Shengfang S Zhou Yixiong Y Jia Renbing R Fan Xianqun X
International journal of biological sciences 20160806 9
Distichiasis presents as double rows of eyelashes arising from aberrant differentiation of the meibomian glands of the eyelids, and it may be sporadic or hereditary. FOXC2 gene mutations in hereditary distichiasis are rarely reported. Here, we examined two generations of a Chinese family with hereditary distichiasis but without lymphedema or other features of LD syndrome. The FOXC2 gene was amplified and sequenced in all family members. Subcellular localization and luciferase assays were perform ...[more]